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Effects of BIIB513 on ischemia-induced arrhythmias and myocardial infarction in anesthetized rats

โœ Scribed by Dongmei Wu; Jean Marie Stassen; Randolph Seidler; Henri Doods

Publisher
Springer
Year
2000
Tongue
English
Weight
155 KB
Volume
95
Category
Article
ISSN
0300-8428

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The electrophysiologic and antiarrhythmic effects of artilide were evaluated in dogs 24 h after myocardial infarction. Artilide (0.1 to 3.0 mgikg or 0.2 to 7.0 p,M/kg iv) prevented programmed stimulation induced ventricular arrhythmias in 9 out of 9 dogs that had demonstrated inducible ventricular a