The effect of inhibiting endogenous brain thromboxane (TXB2) on pentylenetetrazole-induced seizures was studied using the thromboxane synthetase inhibitors OKY-1581 (20 mgikg) and UK 38,485 (50 mgikg). Both compounds selectively decreased ( > 90%) TXB2 production in brain measured after 2 min of con
Effects of Ammonia on Pentylenetetrazole-Induced Seizure Threshold
β Scribed by Kemal Arikan; Tamer Coskun; Bora Guvener; Oznur Oran
- Book ID
- 110400338
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 381 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0885-7490
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Other psychological terms, such as apprehension, anxiety, and fear, will be used in this manuscript to describe more fu]ly the disturbed emotional state induced in these animals. The use of such terms is in agreement with the terminology appearing in current psyehopharmacologicM literature; an inter
Based on previous work examining the effects of dextroamphetamine on pentylenetetrazol (PTZ)-induced clonic seizure threshold, the objective of the present study was to determine the effects of two other dopamine agonists, apomorphine (AP) and piribedil, on PTZ seizures. TDso and LDso values for CD-