Interruption of liver blood flow is often necessary as an operative technique in liver surgery. However, this procedure causes liver damage and can be a factor in postoperative liver failure. Interruption of oxygen and substrate supply and accumulation of metabolites contribute to a great variety of
Effects of amiloride on the mechanical, electrical and biochemical aspects of ischemia-reperfusion injury
✍ Scribed by Ken-ichi Yano; Toru Maruyama; Naoki Makino; Hirosuke Matsui; Takashi Yanaga
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 745 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0300-8177
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To investigate the protective effects of ligustrazine on renal ischemia-reperfusion injury, the influence of ligustrazine injection on plasma superoxide dismutase (SOD), malondialdehyde (MDA), and endothelin-1 (ET-1), as well as changes of morphology of renal tubules, were studied in rat kidney mode
## Abstract Renal ischemia–reperfusion injury occurs in many clinical conditions such as hypovolemic shock, thromboembolism, injury and after renal transplantation. Under these conditions, ROS are considered to be the reason for cellular damage. Bioflavonoids have antioxidant and renoprotective pro