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The protective effect of niacinamide on ischemia-reperfusion-induced liver injury

✍ Scribed by Chao-Fuh Chen; David Wang; Chie Ping Hwang; Hwan Wen Liu; Jeng Wei; Ru Ping Lee; Hsing I. Chen


Publisher
BioMed Central
Year
2001
Tongue
English
Weight
953 KB
Volume
8
Category
Article
ISSN
1021-7770

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We investigated whether intraportal injection of 150 mgkg N-acetylcysteine (NAC) into rats reduced hepatic ischemia-reperfusion injury after 48 hours of cold storage and 2 hours of reperfusion. The organ was isolated and perfused to evaluate liver function. The control group received an intraportal