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Effects of 5-Aza-2′-deoxycytidine on survival and cell cycle progression of L1210 leukemia cells

✍ Scribed by Guy G. Chabot; Richard L. Momparler

Book ID
113238569
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
384 KB
Volume
10
Category
Article
ISSN
0145-2126

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Combinational chemotherapy of L1210 and
Combinational chemotherapy of L1210 and L1210/ARA-C leukemia with 5-AZA-2′-deoxycytidine and β-2′-deoxythioguanosine
✍ Richard L. Momparler; Louise F. Momparler; Johanne Samson 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 359 KB

## Abstract The __in vitro__ and __in vivo__ antineoplastic activity of 5‐AZA‐2'‐deoxycytidine (5‐AZA‐CdR) and β‐2‐deoxythioguanosine (TGdR) on L1210 an L1210/ARA‐C (resistant to cytosine arabinoside) leukemic cells was investigated. 5‐AZA‐CdR was a very potent cytotoxic agent against the L1210 leu