Effects of 1α-hydroxyvitamin D3and 24R,25-dihydroxyvitamin D3on bone remodeling
✍ Scribed by K. Galus; J. Szymendera; A. Zaleski; K. Schreyer
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 354 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1432-0827
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu
To enzymatically synthesize active metabolites of vitamin D3, we screened about 500 bacterial strains and 450 fungal strains, of which 12 strains were able to convert vitamin D 3 to lc~,25-dihydroxyvitamin D3 [lc~,25(OH)2.D3] via 25-hyroxyvitamin D3 [25(OH)Da]. The conversion activity was only detec