๐”– Bobbio Scriptorium
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Effector CD4 and CD8 T Cells and Their Role in the Tumor Microenvironment

โœ Scribed by Sine Hadrup, Marco Donia, Per thor Straten


Book ID
120960237
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
207 KB
Volume
6
Category
Article
ISSN
1875-2292

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta