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CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease

✍ Scribed by Marius Strioga; Vita Pasukoniene; Dainius Characiejus

Book ID
108782925
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
265 KB
Volume
134
Category
Article
ISSN
0019-2805

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta