Maintenance of CD8 effector T cells by CD4 helper T cells eradicates growing tumors and promotes long-term tumor immunity
β Scribed by Cheng-Tao Lin; Ting-Chang Chang; Sheng-Wen Shaw; Po-Jen Cheng; Ching-Tai Huang; Angel Chao; Yung-Kuei Soong; Chyong-Huey Lai
- Book ID
- 116959073
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 399 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0264-410X
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## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex