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Effectiveness of metyrapone in the treatment of acetaminophen toxicity in mice

✍ Scribed by Edward B. Nelson; Mario Montes; Marshall Goldstein


Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
471 KB
Volume
17
Category
Article
ISSN
0300-483X

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πŸ“œ SIMILAR VOLUMES


Effect of aspirin on a subtoxic dose of
✍ L. W. Whitehouse; C. J. Paul; L. T. Wong; B. H. Thomas πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 606 KB

The interaction of 14C-acetaminophen, 150 mg/kg (20 muCi/kg), and aspirin, 200 mg/kg po, was studied in male mice. The radiolabel was rapidly absorbed from the GI tract, achieving maximum blood levels 0.25 hr after oral dosing. Radioactivity in the blood equilibrated rapidly with the tissues and was