✦ LIBER ✦

Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice

✍ Scribed by Lin, Marie C. ;Wang, Er-Jia ;Patten, Chris ;Lee, Mao-Jung ;Xiao, Fang ;Reuhl, Kenneth R. ;Yang, Chung S.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 974 KB
Volume: 11
Category: Article
ISSN: 0887-2082
DOI: 10.1002/(sici)1522-7146(1996)11:1<11::aid-jbt2>3.0.co;2-y

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Fish oil protects mice against acetamino

Fish oil protects mice against acetaminophen hepatotoxicity in vivo

✍ Robert F. Speck; Bernhard H. Lauterburg 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 533 KB

Recent observations suggest that products of nonparenchymal liver cells such as eicosanoids and cytokines might play a role in the expression of liver injury after administration of acetaminophen and other noxious agents. We therefore investigated the effect of a fish oil diet, which results in the

Double-prodrugs of L-cysteine: Different

Double-prodrugs of L-cysteine: Differential protection against acetaminophen-induced hepatotoxicity in mice

✍ Daune L. Crankshaw; Lorelle I. Berkeley; Jonathan F. Cohen; Frances N. Shirota; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB 👁 1 views

## Abstract A series of double‐prodrugs of L‐cysteine, designed to release L‐cysteine in vivo and stimulate the biosynthesis of glutathione (GSH), were synthesized. To evaluate the hepatoprotective effectiveness of these double‐prodrugs, male Swiss‐Webster mice were administered acetaminophen (ACP)

Protective effect of α-lipoic acid again

Protective effect of α-lipoic acid against chloroquine-induced hepatotoxicity in rats

✍ L. Pari; P. Murugavel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB

## Abstract Oral administration of a‐lipoic acid, a metavitamin, was investigated for its possible hepatoprotective effect in Wistar rats against chloroquine‐induced toxicity. Rats were treated orally with __α__‐lipoic acid (10, 30 and 100 mg kg^−1^ day^−1^) for 7 days before a single oral administ

Protective effects of MESNA (2-mercaptoe

Protective effects of MESNA (2-mercaptoethane sulphonate) against acetaminophen-induced hepatorenal oxidative damage in mice

✍ Göksel Şener; Özer Sehirli; Şule Cetinel; Berrak G. Yeğen; Nursal Gedik; Gül Aya 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

## Abstract Acetaminophen, a widely used analgesic and antipyretic, is known to cause hepatic and renal injury in humans and experimental animals when administered in high doses. It was reported that these toxic effects of acetaminophen are due to oxidative reactions that take place during its meta

Protective effect of carrot (Daucus caro

Protective effect of carrot (Daucus carota L.) against lindane - induced hepatotoxicity in rats

✍ P. Balasubramaniam; L. Pari; Venugopal P. Menon 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 82 KB 👁 2 views

Daucus carota commonly known as carrot, is widely used in European folk medicine for the treatment of jaundice and hepatic disorders. Oral administration of carrot extract (25 mL/kg/day) for 30 days produced significant hepatoprotection against lindane (20 mg/kg/day) induced hepatotoxicity in rats.

The protective effect of N-acetylcystein

The protective effect of N-acetylcysteine against cyclosporine A-induced hepatotoxicity in rats

✍ Hasan Kaya; Ahmet Koc; Sadik Sogut; Mehmet Duru; H. Ramazan Yilmaz; Efkan Uz; Ra 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB 👁 1 views

## Abstract The immunosuppressive agent cyclosporine A (CsA) has been reported to exert measurable hepatotoxic effects. One of the causes leading to hepatotoxicity is thought to be reactive oxygen radical formation. The aim of this study was to investigate the effects of __N__‐acetylcysteine (NAC)