A study of MCF-7 human breast cancer cells was undertaken to ascertain the degree of apoptosis induction by paclitaxel and if the induction of apoptosis could be enhanced by caffeine. Paclitaxel (0-20 ng/ml) caused concentration-dependent increases in morphologically identifiable apoptotic cells (up
✦ LIBER ✦
Effectiveness of liposomal paclitaxel against MCF-7 breast cancer cells
✍ Scribed by Heney, Melanie; Alipour, Misagh; Vergidis, Dimitrios; Omri, Abdelwahab; Mugabe, Clement; Th’ng, John; Suntres, Zacharias
- Book ID
- 118169412
- Publisher
- NRC Research Press
- Year
- 2010
- Tongue
- French
- Weight
- 538 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0008-4212
- DOI
- 10.1139/y10-097
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## Abstract In previous studies, we found that progesterone was able to induce the expression of platelet‐derived growth factor (PDGF) in human breast cancer MCF7 cells. Knowing that imatinib mesylate targets PDGF receptor tyrosine kinase activity, the aim of the present study was to examine the ef