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Effectiveness of a new derivative of retinoic acid as differentiating agent on human neuroblastoma cells

✍ Scribed by A.M. Ferreri; E. Magrini; G. Bartolini; M. Orlandi; K. Ammar; P. Perocco; P. Rocchi

Book ID
117658326
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
177 KB
Volume
37
Category
Article
ISSN
0959-8049

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Differentiation-promoting effects of interferon-gamma IFN-y), both alone and in combination with retinoic acid RA), were studied on the human neuroblastoma cell line, LA-N-5. The results show that IFN-y inhibited the growth and induced morphological differentiation in a dose-and timedependent manner