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Synergistic effect of retinoic acid and dehydroepiandrosterone on differentiation of human neuroblastoma cells

✍ Scribed by Francesca Silvagno; Vincenzo Guarnieri; Anna Capizzi; Gian Piero Pescarmona


Book ID
117104902
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
298 KB
Volume
532
Category
Article
ISSN
0014-5793

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Differentiation-promoting effects of interferon-gamma IFN-y), both alone and in combination with retinoic acid RA), were studied on the human neuroblastoma cell line, LA-N-5. The results show that IFN-y inhibited the growth and induced morphological differentiation in a dose-and timedependent manner