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1066 Poster Differentiation promoting and antimitotic activities of a new derivative of retinoic acid on human neuroblastoma cells


Book ID
123116587
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
295 KB
Volume
64
Category
Article
ISSN
0167-8140

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Differentiation-promoting effects of interferon-gamma IFN-y), both alone and in combination with retinoic acid RA), were studied on the human neuroblastoma cell line, LA-N-5. The results show that IFN-y inhibited the growth and induced morphological differentiation in a dose-and timedependent manner