Effect of the fragile X anomaly on body proportions estimated by pedigree analysis
β Scribed by Danuta Z. Loesch; Mark L. Sampson
- Book ID
- 115091400
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 574 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
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## Abstract The effect of the fragile X preβmutation and full mutation categories, and FMRP deficits in these categories, on neurocognitive status, have been assessed in fragile X individuals from 144 extended families, which included fragile X individuals, as well as their nonβfragile X relatives.
Microsatellite markers RS46 (DXS548) and FRAXAC2 flanking the fragile X mutation, an expansion of a (CGG)n repeat within the FMR-1 gene, were typed in 60 unrelated northern and eastern Finnish fragile X families and in a control population from the same geographical region. A significant difference