Incubation of Swiss mouse 3T3 cells at 37Β°C with bovine brain-derived growth factor (BDGF) decreased the cell surface '251-EGF binding activity of these cells by 70-80%. This down-modulation of the EGF receptor by BDGF was time, temperature, and dose dependent. Scatchard plot analysis indicated that
Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts
β Scribed by E. Sturani; R. Brambilla; L. Morello; M.G. Cattaneo; R. Zippel; L. Alberghina
- Book ID
- 115922236
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 326 KB
- Volume
- 255
- Category
- Article
- ISSN
- 0014-5793
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## Abstract The effect of serum on the growth properties of nonβtransformed Balb 3T3 A31 and SV40βtransformed Balb 3T3 A31 was studied. The concentration of serum in the growth medium of nonβtransformed cells had little effect on the initial population doubling time, but did regulate the cell densi