Incubation of Swiss mouse 3T3 cells at 37°C with bovine brain-derived growth factor (BDGF) decreased the cell surface '251-EGF binding activity of these cells by 70-80%. This down-modulation of the EGF receptor by BDGF was time, temperature, and dose dependent. Scatchard plot analysis indicated that
✦ LIBER ✦
The dephosphorylation characteristics of the receptors for epidermal growth factor and platelet-derived growth factor in Swiss 3T3 cell membranes suggest differential regulation of receptor signalling by endogenous protein-tyrosine phosphatases
✍ Scribed by Frank-D. Böhmer; Sylvia-Annette Böhmer; Carl-Henrik Heldin
- Book ID
- 115927537
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 504 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0014-5793
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