Activation of platelet-derived growth factor (PDGF) receptor dephosphorylation in intact Swiss 3T3 cells by elevators of intracellular Ca2+ and cAMP
✍ Scribed by Frank-D. Böhmer; S.-Annette Böhmer
- Book ID
- 115932681
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 418 KB
- Volume
- 391
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Incubation of Swiss mouse 3T3 cells at 37°C with bovine brain-derived growth factor (BDGF) decreased the cell surface '251-EGF binding activity of these cells by 70-80%. This down-modulation of the EGF receptor by BDGF was time, temperature, and dose dependent. Scatchard plot analysis indicated that
## Abstract Platelet‐derived growth factor‐B (PDGF‐B) and its receptors play essential roles in the complex process of blood vessel maturation and they therefore constitute promising targets for therapeutic strategies against blood vessel‐related diseases. Additionally, they are involved in the aut