Effect of the aldose reductase inhibitor fidarestat on experimental diabetic neuropathy in the rat
โ Scribed by Y. Kuzumoto; S. Kusunoki; N. Kato; M. Kihara; P. A. Low
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 338 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The effect of sorbinil (200 mg daily for 4 weeks) was examined in 13 patients, mean age 59.7 years (range 42-72 years), with symptomatic diabetic neuropathy of mean duration 6 year (range 1-18 years). In this double-blind, placebo-controlled crossover trial, studies were made of motor, sensory and a
The effect of two structurally unrelated aldose reductase inhibitors, sorbinil and ponalrestat, on glomerular prostaglandin production and urinary albumin excretion was investigated in rats with diabetes induced by streptozotocin. It was found that both aldose reductase inhibitors, when administered