An immediate depression of the rate of cell proliferation occurred upon addition of glucocorticosteroids to cultures of human skin fibroblasts in the early growth stages. A reduced sensitivity or even insensitivity of the fibroblasts to growth inhibition inhibition was found upon the addition of the
Effect of temperature on mutation in cultured human skin fibroblasts
β Scribed by J.W.I.M. Simons
- Book ID
- 113192355
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 456 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0027-5107
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As previously found, the glucocorticosteroid clobetasol-17-propionate inhibits cell proliferation during the early growth stage of normal baby foreskin fibroblasts and collagen synthesis in confluent cultures of these cells. The degree of inhibition of cell proliferation decreases with increasing ce
Human diploid fibroblasts cultured in Dulbecco's Modified Eagle's medium (DME) were exposed to different concentrations of 15 antibiotics to determine the limiting toxic concentration. The number of cells surviving after antibiotic treatment was given as the index of toxicity. No visible chromosomal