The binding of hydrochlorothiazide and chlorothiazide to milk has been measured. Experiments were carried out at 5, 15, 25, and 37 degrees C on bovine milk samples with fat contents of 0.75, 1.70, and 3.50%, using a wide range of drug concentrations to mimic concentrations encountered when a drug-mi
β¦ LIBER β¦
Effect of temperature and fat content on the solubility of hydrochlorothiazide and chlorothiazide in milk
β Scribed by Panayotis E. Macheras; Michael A. Koupparis; Sophia G. Antimisiaris
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 488 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0022-3549
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## Abstract Preliminary studies by gas chromatography of phytosterols naturally present and added to soya bean oil, indicated that large quantities of these sterols were lost when soya bean oil was exposed to high temperature for a long period. The products which might have been produced as the res