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Effect of temperature and fat content on the solubility of hydrochlorothiazide and chlorothiazide in milk

✍ Scribed by Panayotis E. Macheras; Michael A. Koupparis; Sophia G. Antimisiaris


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
488 KB
Volume
78
Category
Article
ISSN
0022-3549

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The binding of hydrochlorothiazide and chlorothiazide to milk has been measured. Experiments were carried out at 5, 15, 25, and 37 degrees C on bovine milk samples with fat contents of 0.75, 1.70, and 3.50%, using a wide range of drug concentrations to mimic concentrations encountered when a drug-mi

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