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Effect of Telaprevir on the Pharmacokinetics of Midazolam and Digoxin

✍ Scribed by Garg, Varun; Chandorkar, Gurudatt; Farmer, H. Frank; Smith, Frances; Alves, Katia; van Heeswijk, Rolf P. G.

Book ID
121846898
Publisher
Sage Publications
Year
2012
Tongue
English
Weight
282 KB
Volume
52
Category
Article
ISSN
0091-2700

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Abbreviations: AUC, area under the curve; AUC 0-1 , area under the curve from time 0 to infinity; CI, confidence interval(s); CL/F, apparent clearance; C max , maximum concentration; CRU, Clinical Research Unit; CYP3A, cytochrome P450 3A; DN, dose-normalized; F, oral bioavailability; GLS mean ratio(