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Effect of telaprevir on the pharmacokinetics of sirolimus in liver transplant recipients

✍ Scribed by O'Leary, Jacqueline G.; McKenna, Gregory J.; Klintmalm, Göran B.; Davis, Gary L.

Book ID
119994990
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
393 KB
Volume
19
Category
Article
ISSN
1527-6465

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Sirolimus is a new immunosuppressive agent that lacks the nephrotoxicity and neurotoxicity associated with calcineurin inhibitors. [1][2][3] The addition of sirolimus to immunosuppressive protocols may thus allow sparing of calcineurin inhibitors and reduction or elimination of associated toxicities