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Effect of systemic glutathione depletion by buthionine sulfoximine on sensitivity of murine bladder cancer to cytotoxic agents

โœ Scribed by Kan-Ei Lee; Robert D. Mayer; Abraham T.K. Cockett


Book ID
119046536
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
485 KB
Volume
34
Category
Article
ISSN
0090-4295

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๐Ÿ“œ SIMILAR VOLUMES


Cytotoxic effects of glutathione synthes
โœ Robert T. Dorr; James D. Liddil; Michelle J. Soble ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer US ๐ŸŒ English โš– 601 KB

The glutathione (GSH) synthesis inhibitor, buthionine sulfoximine (BSO) was tested for cytotoxicity and thiol depletion in murine and human tumor cells in vitro, and for its antitumor activity and toxicity in vivo. The cell lines used in these studies included murine L-1210 leukemia, human RPMI 8226