The glutathione (GSH) synthesis inhibitor, buthionine sulfoximine (BSO) was tested for cytotoxicity and thiol depletion in murine and human tumor cells in vitro, and for its antitumor activity and toxicity in vivo. The cell lines used in these studies included murine L-1210 leukemia, human RPMI 8226
β¦ LIBER β¦
Toxic effects of extended glutathione depletion by buthionine sulfoximine on murine mammary carcinoma cells
β Scribed by Lyle A. Dethlefsen; John E. Biaglow; V.M. Peck; D.N. Ridinger
- Book ID
- 103721721
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 527 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0360-3016
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