𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of Sugar Molecules on the Viscosity of High Concentration Monoclonal Antibody Solutions

✍ Scribed by Feng He; Christopher E. Woods; Jennifer R. Litowski; Lauren A. Roschen; Himanshu S. Gadgil; Vladimir I. Razinkov; Bruce A. Kerwin

Publisher
Springer US
Year
2011
Tongue
English
Weight
585 KB
Volume
28
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Factors affecting the viscosity in high
Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
✍ Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 372 KB πŸ‘ 1 views

The viscosity profiles of four different IgG 1 molecules were studied as a function of concentration at pH 6.0. At high concentrations, MAb-H and -A showed significantly higher viscosities as compared to MAb-G and -E. Zeta Potential (j) measurements showed that all the IgG 1 molecules carried a net

Viscosity behavior of high-concentration
Viscosity behavior of high-concentration monoclonal antibody solutions: Correlation with interaction parameter and electroviscous effects
✍ Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 318 KB

The purpose of this work was to understand the viscosity behavior of highconcentration monoclonal antibody (mAb) solutions in a wide range of solution conditions and generate guidelines helpful to formulate products with manageable viscosity. The zeta potential and effective isoelectric point (pI) w