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Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma

✍ Scribed by Rabbitts, T. H.; Forster, A.; Hamlyn, P.; Baer, R.


Book ID
109735759
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
820 KB
Volume
309
Category
Article
ISSN
0028-0836

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Chromosomal translocations are found to be a characteristic feature of Burkitt lymphomas. Similar translocations are found in mouse plasmacytomas and both diseases involve interchanges between one of the immunoglobulin loci and DNA in the vicinity of the myc gene. The structure of the myc gene has b