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Defective RNA-mediated c-myc gene silencing pathway in Burkitt’s lymphoma

✍ Scribed by Deepak Kaul; Kavleen Sikand

Book ID
116287688
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
168 KB
Volume
313
Category
Article
ISSN
0006-291X

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Although the Myc family of transcription factors is upregulated in many human tumors, it is unclear which genes are targets for the deregulated Myc. Previous studies suggest that hamster and rat carbamoyl phosphate synthase, aspartate transcarbamylase, dihydroorotase Cad genes are regulated by c-Myc