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Effect of Sodium Butyrate on the Hepatoma Cell Cycle: Possible Use for Cell Synchronization

✍ Scribed by Roeland van Wijk, Lydie Tichonicky and Jaques Kruh

Book ID
125619068
Publisher
Society for In Vitro Biology
Year
1981
Tongue
English
Weight
267 KB
Volume
17
Category
Article
ISSN
1475-2689

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## Abstract The __in vitro__ effect of sodium butyrate (SB) on human hepatoma cell lines PLC/PRF/5, HCC‐M and HCC‐T was investigated. SB was added at the non‐toxic but cytostatic concentration of I mM. In all these cell lines, SB reduced cell proliferation and changed the morphology of the cells in