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Effect of sodium butyrate on the hepatoma cell cycle: Possible use for cell synchronization

✍ Scribed by Roeland van Wijk; Lydie Tichonicky; Jaques Kruh

Book ID
112797801
Publisher
Society for In Vitro Biology
Year
1981
Tongue
English
Weight
432 KB
Volume
17
Category
Article
ISSN
1475-2689

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## Abstract The __in vitro__ effect of sodium butyrate (SB) on human hepatoma cell lines PLC/PRF/5, HCC‐M and HCC‐T was investigated. SB was added at the non‐toxic but cytostatic concentration of I mM. In all these cell lines, SB reduced cell proliferation and changed the morphology of the cells in