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Effect of Sex and AIDS Status on the Plasma and Intrapulmonary Pharmacokinetics of Rifampicin

โœ Scribed by Dr John E. Conte Jr, Jeffrey A. Golden, Juliana E. Kipps, Emil T. Lin, Elisabeth Zurlinden

Book ID
119926564
Publisher
Springer International Publishing AG
Year
2004
Tongue
English
Weight
124 KB
Volume
43
Category
Article
ISSN
0312-5963

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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo