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Effect of roscovitine, a cdk1 inhibitor, and of the presence of oocyte on bovine cumulus cell expansion and cyclooxygenase-2 expression

✍ Scribed by C. Vigneron; F. Nuttinck; C. Perreau; P. Reinaud; G. Charpigny; P. Mermillod

Book ID
111661899
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
131 KB
Volume
65
Category
Article
ISSN
1040-452X

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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in