𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of protein conformation on rate of deamidation: Ribonuclease A

✍ Scribed by Steven J. Wearne; Thomas E. Creighton

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
451 KB
Volume
5
Category
Article
ISSN
0887-3585

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Effect of conformation on the rate of de
Effect of conformation on the rate of deamidation of vancomycin in aqueous solutions
✍ Amy S. Antipas; David G. Vander Velde; Seetharama D. S. Jois; Teruna Siahaan; Va πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 236 KB πŸ‘ 2 views

The instability of vancomycin, a glycopeptide antibiotic, limits its shelf-life because the deamidation of its asparagine residue results in the formation of a zwitterion with limited aqueous solubility. Analysis of the pH-rate profile for vancomycin indicates that the deamidation reaction is notabl

Conformational effects in the reversed-p
Conformational effects in the reversed-phase liquid chromatography of ribonuclease A
✍ S.A. Cohen; K. Benedek; Y. Tapuhi; J.C. Ford; B.L. Karger πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 English βš– 888 KB

This paper examines the reversed-phase liquid chromatographic behavior of ribonuclease A (RNase) using an n-butyl chemically bonded phase and a gradient of 10 mM H3PO4 and l-propanol. At a column temperature of 25 degrees C, a broad band followed by an overlapped late-eluting sharp peak is observed.