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Effect of protease inhibitors on HIV-1 maturation and infectivity

✍ Scribed by D.K Jardine; D.P Tyssen; C.J Birch


Book ID
114145270
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
194 KB
Volume
45
Category
Article
ISSN
0166-3542

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This work presents a chemometric classification for a set of 24 known HIV-1 protease inhibitors, based on two pattern recognition methods widely used in quantitative structure-activity (QSAR) studies: soft independent modeling of class analogy (SIMCA) and Kth nearest neighbors (KNN) with the aim of