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HIV-1 protease inhibitors: effects on HIV-2 replication and resistance

✍ Scribed by Luis Menéndez-Arias; József Tözsér


Book ID
116918768
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
978 KB
Volume
29
Category
Article
ISSN
0165-6147

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Forty-eight methanol and aqueous extracts from Sudanese plants were screened for their inhibitory activity on viral replication. Nineteen extracts showed inhibitory effects on HIV-induced cytopathic effects (CPE) on MT-4 cells. The extracts were further screened against HIV-1 protease (PR) using an