✦ LIBER ✦

Pharmacokinetic Interactions between HIV-1 Protease Inhibitors in Rats: Study on Combinations of Two Kinds of HIV-1 Protease Inhibitors

✍ Scribed by NOBUHITO SHIBATA; YASUHIRO MATSUMURA; HIROYUKI OKAMOTO; YUKO KAWAGUCHI; AKIKO OHTANI; YUKAKO YOSHIKAWA; KANJI TAKADA

Book ID: 111768567
Publisher: Pharmaceutical Press
Year: 2000
Tongue: English
Weight: 113 KB
Volume: 52
Category: Article
ISSN: 2042-7158
DOI: 10.1211/0022357001777379

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In-vitro and in-vivo pharmacokinetic int

In-vitro and in-vivo pharmacokinetic interactions of amprenavir, an HIV protease inhibitor, with other current HIV protease inhibitors in rats

✍ Nobuhito Shibata; Weihua Gao; Hiroyuki Okamoto; Tomoyuki Kishida; Yukako Yoshika 📂 Article 📅 2002 🏛 Pharmaceutical Press 🌐 English ⚖ 226 KB

Evaluation of pharmacokinetic interactio

Evaluation of pharmacokinetic interaction between cetirizine and ritonavir, an HIV-1 protease inhibitor, in healthy male volunteers

✍ G. Peytavin; C. Gautran; C. Otoul; A. C. Cremieux; B. Moulaert; F. Delatour; M. 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 246 KB

Pharmacokinetic study of a tripeptide HI

Pharmacokinetic study of a tripeptide HIV-1 protease inhibitor, KNI-174, in rats after intravenous and intraduodenal administrations

✍ Dr A. Kiriyama; T. Mimoto; Y. Kiso; K. Takada 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 499 KB 👁 2 views

## Abstract Recently, as a new type of anti‐AIDS drug, an HIV‐1 protease inhibitor, KNI‐174, has been synthesized; it shows a potent and selective HIV‐1 protease inhibitory activity __in vitro__. In this study, we developed an HPLC assay system for KNI‐174 in rat plasma and examined the pharmacokin

Kinetic Analysis of the Interaction betw

Kinetic Analysis of the Interaction between HIV-1 Protease and Inhibitors Using Optical Biosensor Technology

✍ Per-Olof Markgren; Markku Hämäläinen; U.Helena Danielson 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 97 KB

The interaction between HIV-1 protease and reversible inhibitors was studied by surface plasmon resonance biosensor technology. The steady-state binding level and the time course of association and dissociation could be observed by measuring the binding of inhibitors injected in a continuous flow of

Interactions of pluronic block copolymer

Interactions of pluronic block copolymers on P-gp efflux activity: Experience with HIV-1 protease inhibitors

✍ Naveed Shaik; Guoyu Pan; William F. Elmquist 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB

The objective was to examine the influence of Pluronic block-copolymers on the interaction between the drug efflux transporter, P-glycoprotein and HIV-1 protease inhibitors (PIs). The ATPase assay determined the effect of various Pluronics on PI-stimulated P-gp ATPase activity. Cellular accumulation

Synthesis, in vitro evaluation, and dock

Synthesis, in vitro evaluation, and docking studies of novel chromone derivatives as HIV-1 protease inhibitor

✍ Jiraporn Ungwitayatorn; Chanpen Wiwat; Weerasak Samee; Patcharawee Nunthanavanit 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 735 KB