๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effect of phenylhydrazine pretreatment on splenectomized rauscher leukemia virus-infected mice

โœ Scribed by Alan Bergson; Professor Joseph Lobue; Albert S. Gordon; Torgny N. Fredrickson

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
234 KB
Volume
10
Category
Article
ISSN
0022-4790

No coin nor oath required. For personal study only.

โœฆ Synopsis

The protective effect of phenylhydrazine pretreatment seen in Rauscher leukemia virus-infected intact mice is not observed when splenectomized mice are used. Such mice succumb to infection even earlier than viral potency controls. Since phenylhydrazine is known to increase both splenic erythropoiesis and hematopoietic stem cell numbers, the results suggest that these two events may be involved in phenylhydrazine prophylaxis.

๐Ÿ“œ SIMILAR VOLUMES

Failure of mice infected with Rauscher l
Failure of mice infected with Rauscher leukemia virus (RLV-A) to develop splenic colonies
โœ Alan Bergson; Professor Joseph Lobue; Torgny N. Fredrickson; Albert S. Gordon ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 433 KB

## Abstract A progressive increase occurs in the CFUโ€S/10^6^ spleen cells with the development of RLVโ€Aโ€induced erythroleukemia. In addition, alteration of the spleen by the RLVโ€A appears to prevent the seeding and development of spleen colonies in infected mice.

Effect of 3-methylcholanthrene and dimet
Effect of 3-methylcholanthrene and dimethylnitrosamine on anchorage dependence of rat fibroblasts chronically infected with rauscher leukemia virus
โœ Nirmal K. Mishra; Wayne L. Ryan ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 579 KB

## Abstract This report describes the loss of anchorage dependence (ADโ€“) after treatment with 3โ€methylcholanthrene or dimethylnitrosamine in rat embryo fibroblasts which normally exhibit anchorage dependence (AD+). The AD+ fibroblasts which were chronically infected with Rauscher leukemia virus sho

In vitro granulocytic stem cell clonogen
In vitro granulocytic stem cell clonogenic capacity of marrow and spleen cells from mice infected with rauscher leukemia virus
โœ Leonard A. Koltun; Hal Broxmeyer; Joseph Lobue; Torgny N. Fredrickson; Professor ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 333 KB

## Abstract Bone marrow and spleen cells from early, midstage, and terminal Rauscher leukemia virus (RLVโ€A)โ€infected erythroleukemic mice were assessed for granulocyte stem cell (CFUโ€c) clonogenic capacity in the semisolid agar culture assay. It was found that marrow CFUโ€c concentrations exceeded n

The effect of murine interferon-alpha/be
The effect of murine interferon-alpha/beta on an established rauscher murine leukemia virus-induced erythroleukemia in balb/c mice
โœ R. A. C. P. Herman; J. Trapman ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 862 KB

## Abstract Rauscher murine leukemia virus (Rโ€MuLV) induces a rapidly developing erythroleukemia in BALB/c mice. Previously, we have shown that mouse interferonโ€ฮฑ/ฮฒ (Mu IFNโ€ฮฑ/ฮฒ) applied shortly after virus inoculation efficiently inhibits the leukemic process (Hekman __et al.__, 1981). Here we desc

Effect of friend leukemia virus on megak
Effect of friend leukemia virus on megakaryocytes and platelets in mice
โœ W. M. Brown; A. A. Axelrad ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 785 KB

## Abstract The thrombocytopenia that follows infection of C3H/Bi mice with Friend leukemia virus (FV) has been investigated. At various times after infection, megakaryocytes in bone marrow and spleen were collected on Nuclepore filters, stained with the Feulgen procedure, and counted. At the same