Effect of phentolamine and obsidan on morphometric indices of the islets of Langerhans in rats receiving alloxan
โ Scribed by T. G. Anishchenko; O. V. Artemenko
- Publisher
- Springer US
- Year
- 1977
- Tongue
- English
- Weight
- 256 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0007-4888
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๐ SIMILAR VOLUMES
Dehydrouramil hydrate hydrochloride (DHU) is an analogue of alloxan which retains the in vivo diabetogenic activity of alloxan but, in contrast to alloxan, is stable in aqueous media at physiological pH. Using rat islets of Langerhans, we have studied the acute effects of DHU on B cell function. Glu
The effects of islet function of addition to the culture medium of rat growth hormone was studied in 4-day cultured islets of Langerhans from normal and hypophysectomised rats. In islets from hypophysectomised rats, rates of insulin release were 34% lower than in control rat islets; rates of insulin