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Effect of alloxan on ?-cells of islets of langerhans in the albino rat

✍ Scribed by Lal, Surendra Kundan

Publisher
Springer-Verlag
Year
1969
Weight
805 KB
Volume
6
Category
Article
ISSN
0001-5563

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Diabetogenic action of alloxan-like comp
Diabetogenic action of alloxan-like compounds: The effect of dehydrouramil hydrate hydrochloride on isolated islets of langerhans of the rat
✍ S. P. C. Tait; M. Poje; B. Rocic; S. J. H. Ashcroft πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 485 KB

Dehydrouramil hydrate hydrochloride (DHU) is an analogue of alloxan which retains the in vivo diabetogenic activity of alloxan but, in contrast to alloxan, is stable in aqueous media at physiological pH. Using rat islets of Langerhans, we have studied the acute effects of DHU on B cell function. Glu