This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m
Effect of permethrin on the induction of sister chromatid exchanges and micronuclei in cultured human lymphocytes
✍ Scribed by Dr. Angustias Herrera; Carmen Barrueco; Covadonga Caballo; Eduardo de la Peña
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 357 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The genetic polymorphisms of glutathione S-trans-(50 mM) and 1.4 (150 mM) times greater among ferases (GSTs), which are involved in the metabolic the GSTT1 null individuals (4.83 at 50 mM, 18.98 inactivation of various toxicants, have been sug-at 150 mM) compared with the GSTT1 positive indigested t
Two studies were conducted to assess the potential for adverse physiologic and genotoxic effects of long-term fluoride ingestion in adults residing in three communities with varying water fluoride levels (0.2 ppm, 1.0 ppm, and 4.0 ppm). All were long-time (> or = 30 years) residents of their respect
## Abstract Frequencies of sister chromatid exchanges (SCE) were analyzed in bone marrow cells of mice injected with mitomycin C (MMC) both before and during infusion with bromodeoxyuridine (BrdU). Administration of MMC at 1, 6.5, and 13 hours after the onset of BrdU infusion resulted in the induct