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Effect of p53 genotype on gene expression profiles in murine liver

✍ Scribed by Suzanne M. Morris; Gregory S. Akerman; Varsha G. Desai; Chen-an Tsai; William H. Tolleson; William B. Melchior Jr.; Chien-Ju Lin; James C. Fuscoe; Daniel A. Casciano; James J. Chen

Book ID
113809145
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
435 KB
Volume
640
Category
Article
ISSN
0027-5107

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## Abstract __In vitro__ studies suggest that __p__53 codon 72 genotype alters the apoptotic capacity of p53 protein, with the 72 arginine (R) form of wild‐type p53 harboring a greater apoptosis‐inducing potential than the 72 proline (P) variant. The aim of this study was to investigate whether the