## Abstract ## BACKGROUND Vascular endothelial growth factor C (VEGFβC) plays an important role in lymphangiogenesis and activates VEGF receptor 3 (VEGFRβ3). By contrast, lymphatic spread is an important prognostic factor in patients with nonsmall cell lung carcinoma (NSCLC). The objective of the
Effect of mitomycin C on concentrations of vascular endothelial growth factor and its receptors in bladder cancer cells and in bladders of rats intravesically instilled with mitomycin C
β Scribed by Avanti Verma; Justin DeGrado; Adam B. Hittelman; Marcia A. Wheeler; Hristos Z. Kaimakliotis; Robert M. Weiss
- Book ID
- 110923064
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 425 KB
- Volume
- 107
- Category
- Article
- ISSN
- 1464-4096
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## Abstract Previous studies have indicated that lymphangiogenesis in solid tumors is associated with lymphatic metastasis. Overexpression of Vascular endothelial growth factor (VEGF)βC plays a major role in lymphangiogenesis in cancers. In the present study, DNA methylation and expression of the _