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Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes

✍ Scribed by Inoue, H.; Arai, Y.; Terauchi, R.; Nakagawa, S.; Saito, M.; Hiraoka, N.; Tsuchida, S.; Matsuki, T.; Mazda, O.; Kubo, T.

Book ID
122215536
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
492 KB
Volume
21
Category
Article
ISSN
1063-4584

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## Abstract ## Objective To determine the effects of hypoxia and reoxygenation on the metabolism of chondrocytes and their response to interleukin‐1Ξ² (IL‐1Ξ²). The study included activation of hypoxia‐inducible factor 1 (HIF‐1), NF‐κB, and activator protein 1 (AP‐1) transcription factors, expressio