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Changes in microstructure and gene expression of articular chondrocytes cultured in a tube under mechanical stress

✍ Scribed by Shuitsu Maeda; Jun Nishida; Takashi Sato; Yoshio Inomata; Tadashi Shimamura; Saburo Horiuchi

Book ID
113732238
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
531 KB
Volume
13
Category
Article
ISSN
1063-4584

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## Abstract ## Objective To determine the effects of hypoxia and reoxygenation on the metabolism of chondrocytes and their response to interleukin‐1Ξ² (IL‐1Ξ²). The study included activation of hypoxia‐inducible factor 1 (HIF‐1), NF‐κB, and activator protein 1 (AP‐1) transcription factors, expressio