𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of Long Chain Isomeric Fatty Acids on Lipid Metabolism in Rats

✍ Scribed by Hølmer, G.

Publisher
John Wiley and Sons
Year
1982
Weight
518 KB
Volume
84
Category
Article
ISSN
0931-5985

No coin nor oath required. For personal study only.

✦ Synopsis

Groups of rats were fed diets withpartially hydrogenatedmarine oils,partially hydrogenated peanut oil, and various nonhydrogenated plant oils including rape seed oil. The deposition of arachidonic acid in phosphatidylcholines (PC) from liver mitochondria membranes was reduced, when partially hydrogenated fats were given, especially for the marine fats containing C20-andC22-monoenes.The content oftrans fatty acidsinPC wassimilarin the twogroups fed partially hydrogenated oils,although no dietary C20-and C22-monoenes were deposited. A corresponding decrease in arachidonic acidwas foundinPC from totalliverand heartofrats,butnosignificantchangeswerefoundinthephospholipiddistribution.ThisdecreaseinC20 : 4 (n-6) was showninvitro to be aconsequence oflowerA6-desaturaseactivityrather than increased peroxisomd P-oxidation of this acid. The long-term lesions, found by others, in hearts of rats fed erucic acid could not be correlated with decreased amounts of arachidonic acid in heart phosphatidylcholines.

📜 SIMILAR VOLUMES

Effect of lactulose on the metabolism of
Effect of lactulose on the metabolism of short-chain fatty acids
✍ Misael Uribe; Octavio Campollo; Christiane Cote 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB 👁 2 views

## Short-chain (C,-C,) fatty acids account for 80%-70% of the anions in the colon. Acetate (C,) is nontoxic in contrast to C,,,,-C, fatty acids (propionate, butyrate, isobutyrate, valerate, and isovalerate). which induce coma in animals and may be important in the patho-gen& of hepatic coma in hum

Effect of extracellular fatty acids on l
Effect of extracellular fatty acids on lipid metabolism in cultured rabbit articular chondrocytes
✍ Masato Nagao; Seiichi Ishii; Yoshihisa Murata; Toyoaki Akino 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 658 KB

Rabbit articular chondrocytes were cultured for 8 h in the presence of various concentrations (5-500 microM) of [14C] oleic, [14C] linoleic, and [3H] arachidonic acids. The radioactive unsaturated fatty acids were incorporated into triacylglycerol (TG) and phosphatidylcholine (PC) in a concentration