Effect of Iontophoretic Current and Application Time on Transdermal Delivery of Ketoprofen in Man
β Scribed by Peter C. Panus; Shirishkumar B. Kulkarni; Jennifer Campbell; William R. Ravis; Ajay K. Banga
- Book ID
- 118109955
- Publisher
- Pharmaceutical Press
- Year
- 1996
- Tongue
- English
- Weight
- 276 KB
- Volume
- 2
- Category
- Article
- ISSN
- 2042-7158
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Iontophoretic transdermal delivery of sumatriptan was investigated in vitro. Among the conditions tested, 0.25 mA/cm 2 and low ionic strength (NaCl 25 mM) was the best experimental condition to increase its transport across the skin. The flux increased 385-fold respective to passive diffusion, thus
The transdermal iontophoretic delivery of Leuprolide, a nonapeptide LHRH agonist was studied with the aim of understanding the mechanisms of iontophoresis. Permeation studies were carried out at pH 4.5 and 7.2, at which the average ionic valence of the drug molecule was roughly 2 and 1, respectively