## Abstract ## Objective Interleukinโ6 (ILโ6) is a pleiotropic cytokine that regulates the immune response, inflammation, and hematopoiesis. Overproduction of ILโ6 plays pathologic roles in rheumatoid arthritis (RA), and the blockade of ILโ6 may be therapeutically effective for the disease. This s
โฆ LIBER โฆ
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
โ Scribed by Josef S Smolen; Andre Beaulieu; Andrea Rubbert-Roth; Cesar Ramos-Remus; Josef Rovensky; Emma Alecock; Thasia Woodworth; Rieke Alten
- Book ID
- 117302691
- Publisher
- The Lancet
- Year
- 2008
- Tongue
- English
- Weight
- 197 KB
- Volume
- 371
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Treatment of rheumatoid arthritis with h
โ
Norihiro Nishimoto; Kazuyuki Yoshizaki; Nobuyuki Miyasaka; Kazuhiko Yamamoto; Sh
๐
Article
๐
2004
๐
John Wiley and Sons
๐
English
โ 163 KB
๐ 3 views
Antiโinterleukin-6 receptor antibody the
โ
Rainer H. Straub; Peter Hรคrle; Seizo Yamana; Takemasa Matsuda; Kiyoshi Takasugi;
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 219 KB
๐ 2 views
Double-blind randomized controlled clini
โ
R. N. Maini; P. C. Taylor; J. Szechinski; K. Pavelka; J. Brรถll; G. Balint; P. Em
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 320 KB
๐ 3 views
A double-blind, placebo-controlled study
โ
Nancy J. Olsen; Raye H. Brooks; John J. Cush; Peter E. Lipsky; E. William St. Cl
๐
Article
๐
1996
๐
John Wiley and Sons
๐
English
โ 654 KB
Objective. To evaluate the efficacy of an antLCD5 ricin-linked immunoconjugate (CD5-IC) in patients with rheumatoid arthritis (RA). Methods. A total of 104 evaluable patients were enrolled in a multicenter, double-blind, multiple-dose, placebo-controlled study of CDS-IC. Results. Treatment with CD
Efficacy and safety of tocilizumab in pa
โ
Shumpei Yokota; Tomoyuki Imagawa; Masaaki Mori; Takako Miyamae; Yukoh Aihara; Sh
๐
Article
๐
2008
๐
The Lancet
๐
English
โ 225 KB
Therapeutic benefit of blocking interleu
โ
E. H. S. Choy; D. A. Isenberg; T. Garrood; S. Farrow; Y. Ioannou; H. Bird; N. Ch
๐
Article
๐
2002
๐
John Wiley and Sons
๐
English
โ 176 KB
๐ 1 views