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Effect of inhibitors of S-Adenosylmethionine decarboxylase on polyamine content and growth of L1210 cells

โœ Scribed by Pegg, Anthony E.; Jones, Daniel B.; Secrist, John A.


Book ID
126453814
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
1021 KB
Volume
27
Category
Article
ISSN
0006-2960

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In the present study we have examined the regulation of the polyamine biosynthetic pathway in a cell line deficient in ornithine decarboxylase (ODC) activity. These cells were unable to grow unless polyamines were provided in their growth medium. Seeding the cells in the absence of polyamines rapidl