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Inhibitors of polyamine biosynthesis. 4. Effects of .alpha.-methyl-(.+-.)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice

✍ Scribed by Newton, Nancy E.; Abdel-Monem, Mahmoud M.


Book ID
123608181
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
682 KB
Volume
20
Category
Article
ISSN
0022-2623

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in vivo effects of 4-amidinoindan-l-one
✍ Bernard Dorhout; Roelf Jakob Te Velde; Harri Ferwerda; Anneke W. Kingma; Elly de 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 558 KB

## Abstract We studied the in vivo effects of 4‐amidinoindan‐l‐one 2′‐amidinohydrazone (CGP 48664A), α‐difluoromethylornithine (DFMO) and a combination of CGP 48664A‐DFMO on tumor growth, cell‐cycle phase distribution and polyamine contents. DBA‐2 mice were inoculated i.p. with 10^5^ L1210 cells on